Reflections on science, technology, and computing — leavened by personal experience


DNA (deoxyribonucleic acid) – it is literally the stuff of life. Thus, understanding how DNA regulates biological processes is key to the mechanics of life and to treating disease at its most fundamental levels.

We need a concord and strategic research investment plan that recognizes the shared importance of HPC and big data. Both warrant investments in basic research, and both need investments in large-scale infrastructure deployments.

Computing research and advanced computing infrastructure are interdependent, yet profoundly different in culture and metrics. As the scale and scope of computing grows, each needs to understand the constraints and needs of the other.

An old joke defines data mining as (insert possessive gesture here) data are mine. Sadly, this hoary saw is more often truthful than humorous. We must find a new way forward that defines the principles and processes for protecting intellectual property while also creating appropriate cultural and economic rewards for data sharing and sustainability. This…

The dramatic growth of research data, the collaborative and competitive nature of international science and engineering research, expectations for economic returns from research investments and disciplinary differences all make this a pressing and difficult problem. Our current, ad hoc approaches are inadequate and not sustainable.

When any new technology appears, there is a great temptation to see it through the lens of the old, either in nomenclature or behavior. As with previous HPC technology transitions, clouds bring a set of technical and cultural challenges , but I believe we are moving down the path of successful adoption.